Joel Schlessinger M.D.

Published works by Joel Schlessinger M.D.

Joel Schlessinger MD evaluates safety, efficacy of clobetasol proprionate for dermatoses

Joel Schlessinger MD evaluates safety, efficacy of clobetasol proprionate for dermatosesJoel Schlessinger MD and colleagues administered a study evaluating the safety and efficacy of clobetasol proprionate for dermatoses in adults and adolescents. The study, “Clobetasol proprionate emulsion formulation foam 0.05%: review of phase II open-label and phase III randomized controlled trials in steroid-responsive dermatoses in adults and adolescents,” was published in the Journal of the  American Academy of Dermatology in September 2008.

Clobetasol proprionate is a topical steroid that is used to treat many skin disorders including psoriasis and eczema. In this study, Joel Schlessinger MD and colleagues used a clobetasol proprionate emulsion formuation foam 0.05% to treat steroid-responsive dermatoses in participants over the age of 6 with mild to severe atopic dermatitis.

In the study, participants received the study drug for 2 weeks and were then evaluated on the efficacy of the drug treating plaque thickness and scaling. Fifty-two patients participated in this study.

After two weeks, it was found that significantly more participants achieved success with the use of clobetasol proprionate emulsion formulation foam 0.05% than those participants that were given vehicle foam. Twenty-seven percent of participants aged 18 years and older saw an improvement in their dermatoses while 47% of participants between the ages of 6 and 12 saw improvement, yet 0% of participants aged between 12 and 18 years saw improvement.

This study only evaluated short-term use of the drug. It was concluded that clobetasol emulsion formuation for dermatoses is a safe and effective treatment for moderate-to-severe atopic dermatitis and mild-to-moderate psoriasis in patients 12 years and older.

To learn about other studies performed and evaluated by Joel Schlessinger MD, visit the Advanced Skin Research Center website here.

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